The upcoming anime adaptation of My Friend’s Little Sister Has It In for Me! is slated to premiere on October 4, 2025, bringing the beloved romantic comedy light novel series to life. The official website and X account for the anime have unveiled a new promotional video, a striking key visual, and details about the theme songs, heightening excitement for the upcoming release. Produced by studio BLADE, this youth rom-com promises a blend of humor, heart, and quirky interpersonal dynamics.
The main promotional video offers a vibrant glimpse into the anime’s world, showcasing its colorful animation and lively character interactions. The video introduces the opening theme, Uza Kawaikute Nani ga Warui! (What’s Wrong With Being Annoyingly Cute!), performed by Karubi Akami, which captures the playful and teasing tone of the series. Complementing it is the ending theme, Hoshi no Kodō (Beat of the Star), sung by Kohana Lam, adding an emotional resonance to the show’s lighter moments. These songs, highlighted in the trailer, set the stage for a series that balances comedic antics with heartfelt connections.
The key visual features the main characters in a dynamic composition, emphasizing the central relationship between the reserved protagonist and the spirited younger sister of his best friend.
The main Japanese voice cast of My Friend’s Little Sister Has It In for Me! includes:
Haruki Ishiya as Akiteru Ooboshi
Sayumi Suzushiro as Iroha Kohinata
Tomori Kusunoki as Mashiro Tsukinomori
Soma Saito as Ozuma Kohinata
Kana Hanazawa as Sumire Kageishi
Studio BLADE, known for its work on character-driven narratives, is handling the animation, ensuring a faithful yet visually engaging adaptation. The official website also confirms that the series will air in Japan starting October 4, with international streaming details expected to follow soon. This premiere marks a significant moment for fans of the original light novel, eager to see how the story translates to the screen.
What is My Friend’s Little Sister Has It In for Me! about?
The anime is based on the light novel series My Friend’s Little Sister Has It In for Me! (ImoUza! in Japan), written by Ghost Mikawa with illustrations by Tomari. First published in 2019 by SB Creative, the series debuted with its first volume and has since grown to ten volumes by 2022, earning a dedicated following for its witty dialogue and relatable characters. The light novel’s success spawned a manga adaptation by Hira Hiraoka, serialized on Square Enix’s Manga UP! service, which further expanded its reach. The series is also available in English through J-Novel Club, making it accessible to a global audience.
J-Novel Club provides the following description of the series:
If a girl teases you, that means she likes you! Unfortunately, Akiteru knows from experience that isn’t the case. Because every girl he interacts with shows him nothing but scorn, and he’s not scored a single date from it! Luckily, he’s more concerned with securing a spot for him and his game-development buddies at his uncle’s business. But when his uncle throws him a condition that involves playing the part of his daughter’s boyfriend, Akiteru has no choice but to take it. What will his best friend’s sister Iroha, who bullies him relentlessly, think of the news?
With its blend of humor, romance, and coming-of-age themes, My Friend’s Little Sister Has It In for Me! is poised to captivate audiences when it debuts on October 4, 2025. The anime’s faithful adaptation, coupled with its infectious energy, makes it a must-watch for fans of the rom-com genre.
