Anime

The Apothecary Diaries Season 3 Anime Drops New Trailer and Ending Theme Song

Maomao and Jinshi face a wider map in The Apothecary Diaries Season 3 as a new ending theme song perofrmed by Eve lands with the new trailer.

The Apothecary Diaries Season 3 anime Credit: © Natsu Hyuuga, Imagica Infos / The Apothecary Diaries Production Committee

A new trailer for The Apothecary Diaries Season 3 has arrived, putting Maomao and Jinshi at the center of widening trouble before the series returns on October 2. The preview also unveils the season’s ending theme, AIYOU by Eve. The official website of The Apothecary Diaries released the footage as the first cour prepares to begin on Friday night in Japan.

The second promotional video follows Jinshi as he confronts his role as imperial younger brother while a rumored immortal woman stirs unrest and a looming disaster hangs over the country. Maomao stands with him as the story moves beyond the rear palace into the streets and toward neighboring lands. The clip teases a mysterious celestial figure, hints at the threat facing the nation, and closes on the current emperor’s remark about Yue choosing a flower, paired with Jinshi’s quiet line of resolve and sorrow.

Akinori Fudesaka is directing Season 3 at OLM, with Wataru Nakagawa serving as assistant director. Norihiro Naganuma handles series composition, while Yuko Kakkihara, Misuzu Chiba, and Hitomi Ogawa write the scripts. Yukiko Nakatani designed the characters, and the score comes from Satoru Kosaki, Kevin Penkin, and Arisa Okehazama. The first cour begins October 2, the second cour follows in April 2027, and an original-story film is scheduled for December 11.

What is The Apothecary Diaries Season 3 about?

The Apothecary Diaries began as a light novel series by Natsu Hyuuga, with illustrations by Touko Shino, after first appearing on the Shōsetsuka ni Narō site. Shufunotomo publishes the books in Japan under the Hero Bunko imprint, and J-Novel Club licenses the novels digitally in English. The adaptation tracks Maomao, a sharp-eyed apothecary drawn into imperial life, as she uses medicine, observation, and stubborn curiosity to unravel court mysteries.

Season 3 picks up after earlier palace upheaval, with Maomao back among familiar streets and Jinshi no longer able to hide from the weight of his true station. Fresh rumors, a strange shrine maiden, and talk of a disaster that could strike the nation pull both of them farther from the inner court. The season widens the map without giving away how those new threads resolve, keeping the focus on investigation, duty, and the uneasy space between the two leads.

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Crunchyroll will stream The Apothecary Diaries Season 3 as the episodes air in Japan, continuing the same window that carried the first two seasons. The new trailer and AIYOU now sit in front of that October 2 start, with the second cour and December film already locked on the calendar.

Source: Official website of The Apothecary Diaries

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